Guggulu (Commiphora mukul) is about mt heighted plant of Burceraceae family. The plant grows wild in the arid, rocky tracts, also in low rainy and hot. Guggulu is an oleo-gum resin which exudes out as a result of injury from the bark of Commiphora wightii (Arnott) Bhandari [syn. Commiphora mukul (Hook. Also listed as: Commiphora mukul, Commifora mukul, Guggulipid Guggul is the common name for the mukul myrrh tree, Commiphora mukul (also known as.

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This study did not report any intestinal distress [ 70 ]. Hypolipidemic and antioxidant effects of Commiphora mukul as an adjunct to dietary therapy in patients with hypercholesterolemia.

Conservation can be effected by knowledge of collection methods and awareness. Simultaneous determination of E- and Z-guggulsterones in dietary supplements containing Commiphora mukul extract guggulipid by liquid chromatography.

Guggultetrols A crystalline material was isolated from the saponified gum resin which was characterized as a mixture of octadecan-1,2,3,4-tetrol 45 Figure 18nonadecan-1,2,3,4-tetrol 46 Figure 18and eicosan-1,2,3,4-tetrol 47 Figure 18 with minor amount of other components, possibly lower C and C and higher C and C homologous tetrols.

Antiarthritic and anti-inflammatory activity of gum guggul Balsamodendron mukul Hook Indian Journal of Physiology and Pharmacology.

Commiphora Mukul Herb Extracts Guggul Gum has been used for a long time in Ayurvedic medicine to treat obesity and other weight related problems. Commiphora Mukul Guggul for Acne. Guggul may affect the risk of bleeding. Please send this link to: Your use of this site indicates your agreement to be bound by our Terms and Conditions. Chemistry of ayurvedic crude drugsā€”II. Muscanone was found to be active against Candida albicans in microbial sensitive assay [ 21 ].

In another study, highly significant reduction in levels of mean serum cholesterol and triglyceride was observed in groups of animals receiving high-fat diet for one month along with guggulu, which clearly demonstrated its hypolipidemic activity.


The antioxidant property of guggulu helped stop the oxidation of cholesterol and subsequent hardening of the arteries, reduced the stickiness of platelet, and also lowered the risk of coronary artery disease [ 45 ]. Panda S, Kar A. The hypolipidemic natural product Commiphora mukul and its component guggulsterone inhibit oxidative modification of LDL. Urizar NL et al. Steroids Isolation of several steroidal constituents has been reported from the gum resin. It has also been mentioned that during the course of using guggulu one should avoid foods that are sour or bitter in taste, alcohol, excessive exercise, physical and mental strain, anger, and exposure to direct sunlight.

Commiphora wightii is sought for its gummy resinwhich is harvested from the plant’s bark through the process of tapping.

Cancer chemopreventive and therapeutic potential of guggulsterone. This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.

Attitudes and knowledge toward natural products safety in the pharmacy setting: Author information Copyright and License information Disclaimer. The ethanolic extract of C. Also, this plant is listed in IUCN list and thus rationale usage of the plant is the need of the hour so that we do not end up depleting this wonder drug of high therapeutic importance. Evidence is lacking to support the use of guggul alone for the management of rheumatoid arthritis.

The Indian Journal of Medical Research. Pharmacological properties of Commiphora wightii Arn. Traditional Uses of Guggulu Guggulu has a long history of use in Ayurveda.

Phytoconstituents of Guggulu Guggulu contains diterpenoids, triterpenoids, steroids, long-chain aliphatic tetrols, aliphatic esters, ferulates, lignans, carbohydrates, and a variety of inorganic ions besides minor amounts of sesamin and other unidentified constituents.

As a result, the levels of other herbs or supplements may be altered in the blood. Guggulu has been used to treat obesity, osteoarthritis, rheumatoid arthritis, gout, facial paralysis, sciatica, constipation, haemorrhoids, liver disorders, inflammation, cyst, cervical lymphadenitis, coronary thrombosis, anaemia, diabetes, urinary calculus, increased frequency and turbidity of urine, and skin diseases [ 3132 ].


Commiphora Mukul Herb Uses, Benefits, Cures, Side Effects, Nutrients

Download Herbpathy App in 3 Easy Steps. Retrieved from ” https: Use cautiously in people taking cholesterol-lowering agents.

Guggulsterones, the lipid-lowering components of guggulu, effectively inhibited in vitro LDL oxidation as discussed under antioxidant action.

It grows up to 2 M.

Commiphora mukul (Guggul)

Absolute stereostructures of polypodane- and octanordammarane-type triterpenes with nitric oxide production inhibitory activity from guggul-gum resins.

Guggulsterone, a potent hypolipidemic, prevents oxidation of low-density lipoprotein. Journal List Anc Sci Life v. Early, low-quality evidence suggests that guggulipid may reduce low-density lipoprotein LDL or “bad” cholesterol and triglycerides, and increase high-density lipoprotein HDL or “good” cholesterol.

Cultivation and Conservation of Guggulu (Commiphora mukul)

Guggul may cause liver failure and inflammation when taken with these. Pharmacological Activity of Guggulu 4. By using this site, you agree to the Terms of Use and Privacy Policy. It is an ingredient of ointment for ulcers [ 2 ]. This activity was also confirmed in other animals including white leghorn chicks, domestic pig, Presbytis monkey, and albino rat [ 1 ]. Unclear scientific evidence for this use D: Commmiphora trials with guggulipid.

Commiphora Mukul Herb Uses, Benefits, Cures, Side Effects, Nutrients

Journal of Medicinal and Aromatic Plant Sciences. There are a large number of commercial polyherbal anti-inflammatory formulations which are using commjphora as the chief ingredient [ 52 ]. Epub Aug Thus the combination of antioxidant and lipid-lowering properties of guggulu makes it especially beneficial against atherogenesis [ 58 ].

Biochemical Systematics and Ecology.